Manoel Island, which can be accessed via a short bridge from Gżira, is largely taken up by boat-building yards and the partly restored Fort Manoel. The island was used as a quarantine zone by the Knights of St John; the shell of their 17th-century plague hospital, the Lazzaretto di San Rocco , can still be seen on the south side. There's a summer fun-fair on the island.
Fort Manoel was built in the early 18th century under Grand Master Manoel de Vilhena, and suffered extensive bomb damage during WWII, when nearby Lazzaretto Creek was used as a submarine base. There are redevelopment plans afoot, but these are controversial, and although restoration has taken place the plans seem to be stalled indefinitely.