At this impressive center you can learn about the duo's epic expedition and the Native Americans who helped them. Check out the beautiful drawings from George Catlin's portfolio.
The same ticket gets you into Fort Mandan , a replica of the fort built by Lewis and Clark, 2.5 miles west (10 miles downstream from the flooded original site). It sits on a lonely stretch of the Missouri River marked by a monument to Seaman, the expedition's dog.
Inside the small but worthwhile information building, look for the display on period medicine, including Dr Rush's 'Thunderclappers.'