You have to see this lakeside institution, which features a stunning winglike addition by Santiago Calatrava. It soars open and closed every day at 10am, noon and 5pm (8pm on Thursday), which is wild to watch (head to the suspension bridge outside for the best view). There are fabulous folk and outsider art galleries, and a sizeable collection of Georgia O'Keeffe paintings. A 2015 renovation added photography and new media galleries to the trove.