In a building that was once a holding facility for slaves newly arrived from Africa, this museum has a small but interesting exhibition on slavery, the slave trade and Afro-Brazilian culture. It's in a sketchy part of the historic center, so ask advice before going there. Be especially alert when walking in this area: the abandoned building directly to the left of Cafua's entrance is a crack den and robberies are not infrequent.
Exhibits include a replica whipping post, and a striking collection of modern wood carvings and statuettes from the parts of West Africa, where the origins of many of São Luís' Afro-Brazilian population lie.